We found that treatment to lower blood sugar levels can be dangerous. 
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The intensive treatment to lower glucose levels in the blood of diabetic patients may be as dangerous as allowing the sugar remains at high level, a study says.
Scientists at Cardiff University in Wales, analyzed the records of nearly 50,000 patients with type 2 diabetes and found a link between lower levels of blood glucose and increased risk of death.
They also found a significant difference in death rates of patients treated with insulin and patients taking tablets., Says the study published in The Lancet.
Changing treatments
Using data from general medical records, researchers identified 27,965 patients with type 2 diabetes whose treatment had been intensified in order to include two oral agents to lower blood glucose: metformin and sulfonylurea.
We need to study further whether the intensification of glucose control with insulin therapy alone increases the risk of death in patients with diabetes.
Dr. Craig Currie, director of research.
20,005 other patients whose treatment was changed and included insulin were added to the study.
We found that patients whose glycated hemoglobin levels (HbA1c) levels, average blood glucose during the past weeks, were of about 7.5% had the lowest risk of death.
But if the levels fell to 6.4%-the lowest levels, both groups of patients showed an increase of over 50% in mortality risk.
And those with the highest levels, 10.6%, the risk of death rose by almost 80%.
The risks, however, seemed particularly pronounced among patients who were being treated with a regimen based on insulin than those who were receiving combination therapy.
